Sex Disparities in Infra-inguinal Prosthetic Bypass for Peripheral Artery Disease

Although prior studies have demonstrated sex-based differences in peripheral arterial disease (PAD), contemporary surgical outcomes remain under-characterized for women compared with men. We aim to discern perioperative between men and PAD who received infra-inguinal prosthetic bypasses. The Infra-Inguinal Bypass Vascular Quality Initiative registry was queried 2010 and2020. evaluated patients infra-inguinal, bypasses occlusive disease, excluding non-occlusive asymptomatic acute limb ischemia, emergent procedures. Baseline demographics, comorbidities, medical management, were using χ2 analysis t test. Socioeconomic status defined distressed community index. patency at 1 year of the same inflow outflow targets, Kaplan-Meier analysis. identified 28,845 bypasses, 36.8% which performed women. Women older had a higher proportion Black race, non-ambulatory status, chronic obstructive pulmonary from socioeconomically “distressed” communities (Table I). Men rate smoking, cardiac heart failure; they also more often on aspirin statin both intervention upon discharge. A females P2Y inhibitors high rates lower extremity percutaneous transluminal angioplasty/stenting Additionally, preoperative vein mapping, although there no significant difference bypass history (coronary or peripheral). presented claudication, distal tibial concurrent ipsilateral endarterectomy II). Alternatively, rest pain tissue loss proximal popliteal targets. did less antibiotic use slightly postoperative infections. Fewer returned home ambulatory There 5-year cumulative survival (89% vs 88.3%; P = .07) 1-year males femoral-above knee (58.1% 61.2%; .069), femoral-below (59.4% 56.7%; .49), femoral-tibial 55.7%; .464) present unique demographic, socioeconomic, pattern associated diminished management advanced severity revascularization. With endovascular intervention, mapping without suggests that is used first potentially due target combined inadequate conduit.